13th International Conference on Advanced Materials and Nanotechnology
ICGM-IAM Université Montpellier, France
Title: 9-3- Single Strand Helicoidal Nanofibers of Photo-Active Polyoxazolines
Biography: Vincent Lapinte
The polyoxazolines, an attractive polymers family characterized by a pseudo-peptidic structure, own bio- and hemocompatibility, low toxicity and furtivity towards immune system - basic properties for biomedical applications. They offer an additional attraction with the ability to self-assembly under various morphologies including spherical nanoparticles, nanowires using hydrogen bonds, dipolar interactions, etc.
In this study we focused on poly(2-methyl-2-oxazoline) decorated by coumarin units, able to photo-activity and able to pi-stacking and further original self-assemblies as already shown with peptides. In a previous work, we demonstrated the UV-activity and the self-organization of amphiphilic diblock and triblock copolyoxazolines in water.(1,2) Herein, well-defined single strand helicoidal fibers were elaborated using amphiphilic graft copolymers. These polymeric filomicelles grown according to crystallization-driven self-assembly (CDSA) between polyoxazoline repetitive units and the coumarin ones. In other experimental conditions, the UV-activity of spherical nanoparticles of the same copolymers were also examined particularly the photo-cross-linking of the nanoparticle core.